Vietnamese Journal of Neurology

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Articles Issue: Vietnamese Journal of Neurology No.42 Nghiên cứu

Some risk factors for recurrent ischemic stroke caused by middle cerebral artery damage

Published: September 23, 2024
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Abstract

Background and Purpose: Recurrent ischemic stroke due to damage to the middle cerebral artery causes deterioration of neurological function and increases the rate of disability, death, and treatment costs many times compared to the first ischemic stroke. Assessing risk factors plays an extremely important role in preventing recurrent ischemic stroke. We have discuss some risk factors for recurrent ischemic stroke caused by middle cerebral artery damage.

Research subjects and methods: Cross-sectional descriptive study on 77 patients with recurrent ischemic stroke due to middle cerebral artery damage at the Neurology Center - Bach Mai Hospital from July 2021 to August 2022.

Summary of review: There were 22 female patients and 55 male patients with an average age of 65 ± 11 years old, predominantly in the age group of 61 - 70 years old (making up 44.2% of the total). The majority of patients experienced their first recurrence (64.9%). The timeframe between the most recent ischemic stroke and the recurrent event ranged from 12 months to 5 years, with the highest occurrence rate at 33.8%. Hypertension has the highest rate among risk factors (88.3%); Hyperlipidemia follows as the second leading risk factor (49.4%). Patients with recurrent ischemic stroke caused by middle cerebral artery damage showed limited effectiveness in recurrence prevention treatment: 68.8% did not adhere to antiplatelet medication or had recently stopped taking them. 81.8% did not consistently receive statin treatment as prescribed. There is a significant difference in clinical recovery levels based on the mRS among patients with and without hypertension (p=0.023); with and without hyperlipidemia (p=0.044); among patients receiving regular and irregular antithrombotic therapy (p < 0.005); among patients receiving regular and irregular statin therapy (p = 0.01).

Conclusion: Our research indicates that recurrent ischemic stroke resulting from middle cerebral artery damage presents a higher number of risk factors, and the efficacy of recurrence prevention treatment is suboptimal.

References

1.
Mohan KM, Wolfe CDA, Rudd AG, Heuschmann PU, Kolominsky-Rabas PL, Grieve AP. Risk and Cumulative Risk of Stroke Recurrence. Stroke. 2011;42(5):1489-1494.
2.
Boulanger M, Béjot Y, Rothwell PM, Touzé E. Long-Term Risk of Myocardial Infarction Compared to Recurrent Stroke After Transient Ischemic Attack and Ischemic Stroke: Systematic Review and Meta-Analysis. J Am Heart Assoc. 2018;7(2).
3.
Hankey GJ. Long-term outcome after ischaemic stroke/transient ischaemic attack. Cerebrovasc Dis. 2003;16 Suppl 1:14-19.
4.
Jørgensen HS, Nakayama H, Reith J, Raaschou HO, Olsen TS. Stroke recurrence: predictors, severity, and prognosis. The Copenhagen Stroke Study. Neurology. 1997;48(4):891-895.
5.
Nguyen Thi Thu Huyen, Nguyen Van Chuong. Research on Clinical Characteristics, Neuroimaging and Some Risk Factors in Patients with Recurrent Ischemic Stroke. Doctoral thesis in medicine. 2012.
6.
Xu G, Liu X, Wu W, Zhang R, Yin Q. Recurrence after ischemic stroke in chinese patients: impact of uncontrolled modifiable risk factors. Cerebrovasc Dis. 2007;23(2-3):117-120.
7.
Nguyen Van Long. Research on Clinical Characteristics and Some Risks in Patients with Early Recurrent Cerebral Infarction. Specialized thesis level II. 2019.
8.
Khanevski AN, Bjerkreim AT, Novotny V, et al. Recurrent ischemic stroke: Incidence, predictors, and impact on mortality. Acta Neurol Scand. 2019;140(1):3-8.
9.
Dinh Huu Hung. Risk of Recurrence After Acute Ischemic Stroke According to Stratification of Some Related Factors. Doctoral thesis in Medicine. 2014.
10.
Kleindorfer DO, Towfighi A, Chaturvedi S, et al. 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association. Stroke. 2021;52(7):e364-e467. doi:10.1161/STR.0000000000000375
11.
Penado S, Cano M, Acha O, Hernández JL, Riancho JA. Atrial fibrillation as a risk factor for stroke recurrence. Am J Med. 2003;114(3):206-210. doi:10.1016/s0002-9343(02)01479-1
12.
Chen J, Li S, Zheng K, et al. Impact of Smoking Status on Stroke Recurrence. J Am Heart Assoc. 2019;8(8):e011696. doi:10.1161/JAHA.118.011696

Authors

  • Nguyen Thi Huyen
  • Phan Van Duc
  • Nguyen Thanh Binh

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