Vietnamese Journal of Neurology

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Articles Issue: Vietnamese Journal of Neurology No.43 Nghiên cứu

Prognosic factors of patients with acute supratentorial cerebral hemorrhage due to hypertension

Published: November 5, 2024
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Abstract

Objectives: Comments on the relationship of prognostic factors in patients with acute supratentorial cerebral hemorrhage due to hypertension.

Subjects and method: A cross-sectional, prospective descriptive study was conducted on 150 patients diagnosed with acute supratentorial cerebral hemorrhage due to hypertension, admitted for inpatient treatment at the Neurology Center, Bach Mai Hospital from August 1, 2023 to July 31, 2024.

Results: The rate of patients with good outcome after 3 months (73.3%). In terms of prognostic factors, the study showed that in the age group ≤ 60 years old, the rate of poor outcome was 18.1%, the group > 60 years old had a rate of poor outcome of 34.6%. Thus, in the age group > 60 years old, the outcome was worse, this difference was statistically significant with p<0.05. In our study, there was no statistically significant difference in outcome at day 90 between patients with a history of hypertension, diabetes, coronary artery disease, antiplatelet drugs, smoking, alcohol consumption and patients without this history. In the group without cerebral hemorrhage, the rate of patients with poor outcome was 18.8%; while in the group with cerebral hemorrhage, this rate was 36.9%, this difference was statistically significant with p<0.05. In the group with no hematoma volume < 30 ml, the rate of patients with poor outcome was 14.1%; meanwhile, in the group with hematoma volume ≥ 30 ml, this rate was 100%, this difference was statistically significant with p < 0.01. In the group with Glasgow score at admission ≥ 14 points, the rate of patients with poor outcome was 14.4%; meanwhile, in the group with Glasgow score at admission < 14 points, the rate of patients with poor outcome was 71.9%, this difference was statistically significant with p < 0.01.

Conclusion: Studying 150 patients with acute supratentorial cerebral hemorrhage due to hypertension treated at the Neurology Center - Bach Mai Hospital from August 1, 2023 to July 31, 2024, we drew the following conclusions: factors leading to poor outcomes for patients with acute cerebral hemorrhage due to hypertension include age > 60, hematoma volume ≥ 30 ml, Glasgow score at admission below 14 points, and intraventricular hemorrhage.

References

1.
Nag C, Das K, Ghosh M, Khandakar MR. Prediction of Clinical Outcome in Acute Hemorrhagic Stroke from a Single CT Scan on Admission. North Am J Med Sci. 2012;4(10):463-467. doi:10.4103/1947-2714.101986
2.
Labovitz DL, Halim A, Boden-Albala B, Hauser WA, Sacco RL. The incidence of deep and lobar intracerebral hemorrhage in whites, blacks, and Hispanics. Neurology. 2005;65(4):518-522. doi:10.1212/01.wnl.0000172915.71933.00
3.
Falcone GJ, Biffi A, Brouwers HB, et al. Predictors of hematoma volume in deep and lobar supratentorial intracerebral hemorrhage. JAMA Neurol. 2013;70(8):988-994. doi:10.1001/jamaneurol.2013.98
4.
Falcone GJ, Woo D. Genetics of Spontaneous Intracerebral Hemorrhage. Stroke. 2017;48(12):3420-3424. doi:10.1161/STROKEAHA.117.017072
5.
Fisher CM. Lacunar strokes and infarcts: a review. Neurology. 1982;32(8):871-876. doi:10.1212/wnl.32.8.871
6.
Falcone GJ, Biffi A, Devan WJ, et al. Burden of risk alleles for hypertension increases risk of intracerebral hemorrhage. Stroke. 2012;43(11):2877-2883. doi:10.1161/STROKEAHA.112.659755
7.
Falcone GJ, Biffi A, Devan WJ, et al. Burden of blood pressure-related alleles is associated with larger hematoma volume and worse outcome in intracerebral hemorrhage. Stroke. 2013;44(2):321-326. doi:10.1161/STROKEAHA.112.675181
8.
Đỗ Văn Tài. Đánh giá hiệu quả điều trị hạ áp tích cực ở bệnh nhân xuất huyết não giai đoạn cấp. Luận án chuyên khoa cấp II. Đại học Y dược Thành phố Hồ Chí Minh; 2016.
9.
Anderson CS, Heeley E, Huang Y, et al. Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage. N Engl J Med. 2013;368(25):2355-2365. doi:10.1056/NEJMoa1214609
10.
Nguyễn Duy Mạnh. Nghiên cứu kết quả điều trị hạ huyết áp tích cực trong chảy máu não nguyên phát do tăng huyết áp giai đoạn cấp. Luận án tiến sĩ y học. Viện Nghiên cứu khoa học Y Dược lâm sàng 108; 2018.

Authors

Ha Huu Quy Tran Quang Binh

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