Abstract
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, characterized by chronic inflammation, demyelination (loss of myelin sheath), nerve fiber loss, and potential relapses or progression. Demyelinated patches often develop at different times and in different locations within the central nervous system (spatially and temporally scattered).
Symptoms and neurological signs are manifestations of the damage and spread of demyelinated lesions, primarily occurring in the white matter of the brain, spinal cord, or optic nerves.